Radioactive measurement: Combustion or Dissolving - Radioactive measurement of feces, blood, liver, brain or fat tissue, a Comparison of Dissolving with Combustion
E. Beek-van Velzen (Solvay Pharmaceutical Research Laboratories, C.J. van Houtenlaan 36, 1381 CP Weesp, The Netherlands)

Bioanalytical Method Development for Therapeutic Peptides
Erin Chambers (Waters Corporation)

A Leap Forward in Sensitivity and Selectivity for PAH Analysis using GC-APLI-TOF/MS
Rob van der Heijden¹, Patrick van Houts¹, George McLeod², Thomas Arthen-Engeland³, Carsten Baessmann³, Armin Holle³ (1. Bruker Daltonics BV, PO Box 88, 1530 AB, Wormer, The Netherlands, 2. Bruker Daltonics, Coventry, United Kingdom and 3. Bruker Daltonik GmbH, Bremen, Germany)

Improved Peptide Identification with an Ultra High Resolution Quadrupole Time of Flight MS (maXis)
Patrick van Houts¹, Rob van der Heijden¹, Markus Lubeck², Marina Behrens², Andrea Schneider², Carsten Baessmann² and Oliver Raether² (1. Bruker Daltonics, Wormer, The Netherlands and 2. Bruker Daltonik, Bremen, Germany)

Detection of Metabolites in Urine at Microdosing Levels in Rats Using LC-MS/MS
Carmai Seto¹, Tanya Gamble¹, Takeo Sakuma¹, Jinsong Ni², Fred Ouyang², Devin Welty² and Andrew Acheampong² (1. Applied Biosystems/MDS Analytical Technologies, 71 Four Valley Drive, Concord, Ontario, Canada and 2. Dept of Drug Safety Evaluation, Allergan, Irvine, CA, USA)

High Throughput Screening of GSH Adducts Using Hybrid Linear Ion Trap Systems Coupled with Fast Chromatography at Clinically Relevant Dose Concentrations
Hua-fen Liu¹, Hesham Ghobarah² , Renee Huang¹, Jens Dahlmann³ and Elliott Jones¹ (Applied Biosystems, part of Life Technologies, (1) Foster City, USA, (2) Concord, Canada, (3) Darmstadt, Germany)

Simultaneous quantification of testosterone and androstenedione in human serum using LC-MS/MS
E. Joos^1,2, J. Van Bocxlaer², M. Vandermarliere¹ and K. Croes¹ (1. Clinical Laboratory, AZ Groeninge, Reepkaai, B-8500 Kortrijk. Belgium & 2. Laboratory for Medical Biochemistry and Clinical Analysis, Fac. Pharm. Sci., Ghent University, Harelbekestraat 72, B-9000 Gent. Belgium)

CHIRAL LC-MS-MS DETERMINATION OF (R)- AND (S)-CITALOPRAM IN HUMAN PLASMA SAMPLES
E. Mallat, V. Jas, J. Flik, M. Boterman, K. de Jonge (Analytisch Biochemisch Laboratorium (ABL) BV, Scholtenstraat 7, Assen, The Netherlands)

A sensitive LC-MS/MS method for the separate quantification of gentamicin C1, C1a, C2 and C2a in bovine tissue.
M. Boterman, M.J. Dröge, F. Oostebring, F. Venema & E. Oosting (Analytisch Biochemisch Laboratorium (ABL) BV, Assen, The Netherlands)

A sensitive automated online SPE-LC-MS/MS method for the quantitative determination of ivermectin B1a in bovine plasma.
M. Boterman¹, M.J. Dröge¹, F. Oostebring¹, M.A.H. Boezeman² and E. Oosting¹ (1. Analytisch Biochemisch Laboratorium (ABL) BV, Assen, The Netherlands and 2. Farma Research Animal Health (FRAH) BV, Nijmegen, The Netherlands)

New UHPLC systems from Eksigent Technologies for improved performance in LC/MS
Rein Reitsma (Separations Analytical Instruments)

DRIED BLOOD SPOTS FOR TK/PK AND BIOMARKER ANALYSIS AND 3R
Elwin Verheij (TNO Quality of Life, PO Box 360, 3700 AJ Zeist)

Generic solid phase extraction procedure for the quantitative analysis of peptides in plasma
H. Korthals, H. Gerritsen, R. Brust-van Schaik and B. Buscher* (TNO Quality of Life, Zeist, The Netherlands)

EX VIVO HUMAN SKIN MODEL FOR PHOTOGENOTOXICITY TESTING
AA Reus, FAA van Acker, CAM Krul (TNO Quality of Life, Zeist, The Netherlands)

Monitoring Matrix EffectsM in Biological Samples Utilizing Dual Scan MRM Mode Mass Spectrometry
Paul D Rainville, Joanne Mather, Robert S Plumb, Jing Lin (Waters Corporation, Milford, MA)

The CMA 64 IView microdialysis Catheter
Noud Grimberg (Aurora Borealis Control B.V., Postbus 2, 7760 AA Schoonebeek)

Accuracy of incurred sample results, the final validation challenge in quantitative bioanalysis ?
Theo de Boer, Marjan Hagenouw, Rudy Francke and Jaap Wieling (Xendo Drug Development B.V., Hanzeplein 1, NL-9713 GZ Groningen, The Netherlands)

Application of Dried Blood Spot sampling within clinical trials: Feasibility study of pardoprunox, a potent anti-Parkinson Drug
O.A.M. Brockhoff¹, P.H. van Amsterdam¹, J. Thomson², C. Troupe³ (1. Solvay Pharmaceuticals, Global Bioanalytics Department, Weesp, The Netherlands 2. Aptuit Inc, Riccarton, Scotland, 3. Quintiles Laboratories, Marietta, GA, USA)

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Last update
06-Nov-09